DPP4-inhibitor improves neuronal insulin receptor function, Brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption

High-fat diet (HFD) consumption has been demonstrated to cause peripheral and neuronal insulin resistance, and brain mitochondrial dysfunction in rats. Although the dipeptidyl peptidase-4 inhibitor, vildagliptin, is known to improve peripheral insulin sensitivity, its effects on neuronal insulin res...

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Bibliographic Details
Main Authors: Noppamas Pipatpiboon, Hiranya Pintana, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84874525661&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/52955
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Institution: Chiang Mai University