Roles of p38-MAPK in insulin resistant heart: Evidence from bench to future bedside application

• Main Authors: Sarawut Kumphune, Siriporn Chattipakorn, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84884268759&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52964
• Institution: Chiang Mai University

Insulin resistance is associated with the impairment of the response of insulin receptor to insulin, resulting in the reduction of glucose uptake, leading to the alteration of myocardial glucose metabolism, impairment of cardiac electrophysiology, and increased susceptibility to ischemia-induced myo...