Isopimarane diterpenes and flavan derivatives from the twigs of Caesalpinia furfuracea

The first phytochemical investigation of Caesalpinia furfuracea twigs led to the isolation and identification of four new compounds including two isopimarane diterpenes, caesalfurfuric acids A (1) and B (2), and two flavans, (2R)-caesalflavans A (5) and B (6), together with four known compounds, 4-e...

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Bibliographic Details
Main Authors: Ittipon Siridechakorn, Sarot Cheenpracha, Thunwadee Ritthiwigrom, Wong Phakhodee, Suwanna Deachathai, Theeraphan Machan, Nirun Ruankeaw, Surat Laphookhieo
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84891603038&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53090
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Institution: Chiang Mai University
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Summary:The first phytochemical investigation of Caesalpinia furfuracea twigs led to the isolation and identification of four new compounds including two isopimarane diterpenes, caesalfurfuric acids A (1) and B (2), and two flavans, (2R)-caesalflavans A (5) and B (6), together with four known compounds, 4-epi-isopimaric acid (3), methyl (E)-3-(3,4-dihydroxyphenyl)acrylate (4), (E)-resveratrol (7) and oxyresveratrol (8). Their structures were elucidated by intensive spectroscopic analysis. Compound 1 was found to exhibit antibacterial activity against MRSA SK1 with an MIC value of 16 μg/mL. © 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.