A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari

A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n-BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on...

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Main Authors: Wasana Prapalert, Dammrong Santiarworn, Saisunee Liawruangrath, Boonsom Liawruangrath, Stephen G. Pyne
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/53126
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-531262018-09-04T10:00:36Z A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari Wasana Prapalert Dammrong Santiarworn Saisunee Liawruangrath Boonsom Liawruangrath Stephen G. Pyne Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n-BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on the basis of their spectroscopic data. These compounds were isolated for the first time from P. lanceolaria. The EtOAc and n-BuOH fractions also possessed significant antioxidant activity with IC50 values of 57 and 50 μg/mL, respectively (DPPH method), whereas 1 had an IC50 value of 23 μg/mL. 2018-09-04T09:44:04Z 2018-09-04T09:44:04Z 2014-01-01 Journal 15559475 1934578X 2-s2.0-84911129382 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84911129382&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53126
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Agricultural and Biological Sciences
Medicine
Pharmacology, Toxicology and Pharmaceutics
spellingShingle Agricultural and Biological Sciences
Medicine
Pharmacology, Toxicology and Pharmaceutics
Wasana Prapalert
Dammrong Santiarworn
Saisunee Liawruangrath
Boonsom Liawruangrath
Stephen G. Pyne
A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
description A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n-BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on the basis of their spectroscopic data. These compounds were isolated for the first time from P. lanceolaria. The EtOAc and n-BuOH fractions also possessed significant antioxidant activity with IC50 values of 57 and 50 μg/mL, respectively (DPPH method), whereas 1 had an IC50 value of 23 μg/mL.
format Journal
author Wasana Prapalert
Dammrong Santiarworn
Saisunee Liawruangrath
Boonsom Liawruangrath
Stephen G. Pyne
author_facet Wasana Prapalert
Dammrong Santiarworn
Saisunee Liawruangrath
Boonsom Liawruangrath
Stephen G. Pyne
author_sort Wasana Prapalert
title A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
title_short A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
title_full A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
title_fullStr A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
title_full_unstemmed A New 1,6-Benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
title_sort new 1,6-benzoxazocine-5-one alkaloid isolated from the aerial parts of peristrophe lanceolari
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84911129382&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53126
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