Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)

The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nig...

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Main Authors:	Ittipon Siridechakorn, Wisanu Maneerat, Tawanun Sripisut, Thunwadee Ritthiwigrom, Sarot Cheenpracha, Surat Laphookhieo
Format:	Journal
Published:	2018
Subjects:	Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84896311465&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53149
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Institution:	Chiang Mai University

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spelling	th-cmuir.6653943832-531492018-09-04T09:46:18Z Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae) Ittipon Siridechakorn Wisanu Maneerat Tawanun Sripisut Thunwadee Ritthiwigrom Sarot Cheenpracha Surat Laphookhieo Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nigrolineabiphenyl B (4); and four xanthones, 1,3,6-trihydroxy-8-isoprenyl-7- methoxyxanthone (5), morusignin K (6), 1,5-dihydroxyxanthone (7), and 1,7-dihydroxyxanthone (8), were isolated from the acetone extract of the twigs of a Garcinia sp. Their structures were characterized extensively by 1D and 2D NMR spectroscopy and HR-EI-MS. The cytotoxicity of the two new biphenyls against the oral cavity cancer (KB) and the breast cancer (MCF7) cell lines was also evaluated. © 2014 Phytochemical Society of Europe. 2018-09-04T09:44:18Z 2018-09-04T09:44:18Z 2014-01-01 Journal 18767486 18743900 2-s2.0-84896311465 10.1016/j.phytol.2014.02.004 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84896311465&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53149
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology
spellingShingle	Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology Ittipon Siridechakorn Wisanu Maneerat Tawanun Sripisut Thunwadee Ritthiwigrom Sarot Cheenpracha Surat Laphookhieo Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
description	The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nigrolineabiphenyl B (4); and four xanthones, 1,3,6-trihydroxy-8-isoprenyl-7- methoxyxanthone (5), morusignin K (6), 1,5-dihydroxyxanthone (7), and 1,7-dihydroxyxanthone (8), were isolated from the acetone extract of the twigs of a Garcinia sp. Their structures were characterized extensively by 1D and 2D NMR spectroscopy and HR-EI-MS. The cytotoxicity of the two new biphenyls against the oral cavity cancer (KB) and the breast cancer (MCF7) cell lines was also evaluated. © 2014 Phytochemical Society of Europe.
format	Journal
author	Ittipon Siridechakorn Wisanu Maneerat Tawanun Sripisut Thunwadee Ritthiwigrom Sarot Cheenpracha Surat Laphookhieo
author_facet	Ittipon Siridechakorn Wisanu Maneerat Tawanun Sripisut Thunwadee Ritthiwigrom Sarot Cheenpracha Surat Laphookhieo
author_sort	Ittipon Siridechakorn
title	Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_short	Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_full	Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_fullStr	Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_full_unstemmed	Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_sort	biphenyl and xanthone derivatives from the twigs of a garcinia sp. (clusiaceae)
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84896311465&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53149
_version_	1681424081563418624

Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)

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