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__    __    ______    ______    ______    ______  
\ \\ / //  /_   _//  /_   _//  /_   _//  /_   _// 
 \ \/ //    -| ||-   `-| |,-    -| ||-   `-| |,-  
  \  //     _| ||_     | ||     _| ||_     | ||   
   \//     /_____//    |_||    /_____//    |_||   
    `      `-----`     `-`'    `-----`     `-`'

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Text this: Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance