Effect of topology of poly(L-lactide-co-ε-caprolactone) scaffolds on the response of cultured human umbilical cord Whartons jelly-derived mesenchymal stem cells and neuroblastoma cell lines

• Main Authors: Boontharika Thapsukhon, Donraporn Daranarong, Puttinan Meepowpan, Nuttee Suree, Robert Molloy, Kewalin Inthanon, Weerah Wongkham, Winita Punyodom
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Materials Science; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84903783670&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53183
• Institution: Chiang Mai University

In this study, for the first time, a biodegradable poly(L-lactide-co- ε-caprolactone), PLC 67:33 copolymer was developed for use as temporary scaffolds in reconstructive nerve surgery. The effect of the surface topology and pore architecture were studied on the biocompatibility for supporting the gr...