Changes in renal function associated with oral emtricitabine/tenofovir disoproxil fumarate use for HIV pre-exposure prophylaxis

• Main Authors: Marc M. Solomon, Javier R. Lama, David V. Glidden, Kathleen Mulligan, Vanessa McMahan, Albert Y. Liu, Juan Vicente Guanira, Valdilea G. Veloso, Kenneth H. Mayer, Suwat Chariyalertsak, Mauro Schechter, Linda Gail Bekker, Esper Georges Kallás, David N. Burns, Robert M. Grant
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84898016347&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53611
• Institution: Chiang Mai University

Objective: Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis decreases sexual acquisition of HIV infection. We sought to evaluate the renal safety of TDF in HIV-uninfected persons. Design and methods: The Iniciativa Profilaxis Pre-Exposición (iPrEx) study randomly assigned 2499 HIV-serone...