Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy

Background: With effective highly active antiretroviral therapy (HAART), perinatally HIV-infected children are living longer through adolescence. Methods: We conducted a cross-sectional study of perinatally HIV-infected adolescents, aged 11 to 18 years. Demographically matched controls were also enr...

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Main Authors: Orawan Louthrenoo, Peninnah Oberdorfer, Virat Sirisanthana
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/53614
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-536142018-09-04T09:58:06Z Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy Orawan Louthrenoo Peninnah Oberdorfer Virat Sirisanthana Immunology and Microbiology Medicine Background: With effective highly active antiretroviral therapy (HAART), perinatally HIV-infected children are living longer through adolescence. Methods: We conducted a cross-sectional study of perinatally HIV-infected adolescents, aged 11 to 18 years. Demographically matched controls were also enrolled. The adolescents completed the Youth Self-Report (YSR), while the caregivers filled out the Child Behavior Checklist (CBCL), to determine emotional and behavioral problems. Results: The sample included 50 HIV-infected adolescents and 56 controls. The internalizing problem scores from the YSR were significantly higher in the HIV-infected group than those in the control group (13.76 versus 9.95, P .02). The total competence scores, from both the self-report and the caregiver report in the HIV-infected group, were significantly lower than those of the control group (P .005 and .001). Conclusion: Although HAART has prolonged the survival of HIV-infected children, they remain at increased risk of psychosocial problems as well as impaired social functioning. 2018-09-04T09:52:52Z 2018-09-04T09:52:52Z 2014-01-01 Journal 23259582 23259574 2-s2.0-84899519920 10.1177/2325957413488171 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84899519920&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53614
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Immunology and Microbiology
Medicine
spellingShingle Immunology and Microbiology
Medicine
Orawan Louthrenoo
Peninnah Oberdorfer
Virat Sirisanthana
Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy
description Background: With effective highly active antiretroviral therapy (HAART), perinatally HIV-infected children are living longer through adolescence. Methods: We conducted a cross-sectional study of perinatally HIV-infected adolescents, aged 11 to 18 years. Demographically matched controls were also enrolled. The adolescents completed the Youth Self-Report (YSR), while the caregivers filled out the Child Behavior Checklist (CBCL), to determine emotional and behavioral problems. Results: The sample included 50 HIV-infected adolescents and 56 controls. The internalizing problem scores from the YSR were significantly higher in the HIV-infected group than those in the control group (13.76 versus 9.95, P .02). The total competence scores, from both the self-report and the caregiver report in the HIV-infected group, were significantly lower than those of the control group (P .005 and .001). Conclusion: Although HAART has prolonged the survival of HIV-infected children, they remain at increased risk of psychosocial problems as well as impaired social functioning.
format Journal
author Orawan Louthrenoo
Peninnah Oberdorfer
Virat Sirisanthana
author_facet Orawan Louthrenoo
Peninnah Oberdorfer
Virat Sirisanthana
author_sort Orawan Louthrenoo
title Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy
title_short Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy
title_full Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy
title_fullStr Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy
title_full_unstemmed Psychosocial functioning in adolescents with perinatal HIV infection receiving highly active antiretroviral therapy
title_sort psychosocial functioning in adolescents with perinatal hiv infection receiving highly active antiretroviral therapy
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84899519920&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53614
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