The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients

Objective: To compare the postprandial plasma glucose level after diabetic specific formula (DSF) and standard formula (SF) administration in type 2 diabetic patients. Material and Method: Thirty type 2 diabetic patients were included in the present randomized, controlled, double-blind, cross-over s...

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Main Authors: Supawan Buranapin, Sanguansak Siangruangsang, Vipawan Chantapanich, Natavuth Hengjeerajarus
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/53780
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spelling th-cmuir.6653943832-537802018-09-04T09:57:36Z The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients Supawan Buranapin Sanguansak Siangruangsang Vipawan Chantapanich Natavuth Hengjeerajarus Medicine Objective: To compare the postprandial plasma glucose level after diabetic specific formula (DSF) and standard formula (SF) administration in type 2 diabetic patients. Material and Method: Thirty type 2 diabetic patients were included in the present randomized, controlled, double-blind, cross-over study. Subjects received DSF and isocaloric SF as a bolus administration of 400 mL while continuing their anti-diabetic medications. Venous blood samples were collected and analyzed to assess plasma glucose levels at pre- and at 30, 60, 90, 120, and 180 min post-administration of the formulas. Results: Postprandial glucose profiles were significantly lower with DSF compared to SF administration determined as a mean glucose concentration at 2-hour post-administration. The glucose area under the curve (AUC) after DSF consumption was 33% lower than the AUC after SF consumption, p<0.001. Conclusion: Use of DSF resulted in a significantly lower postprandial rise in plasma glucose concentrations than using SF. It should be the preferred option in diabetic patients who need nutritional support. 2018-09-04T09:57:36Z 2018-09-04T09:57:36Z 2014-01-01 Journal 01252208 2-s2.0-84904738909 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84904738909&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53780
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Supawan Buranapin
Sanguansak Siangruangsang
Vipawan Chantapanich
Natavuth Hengjeerajarus
The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients
description Objective: To compare the postprandial plasma glucose level after diabetic specific formula (DSF) and standard formula (SF) administration in type 2 diabetic patients. Material and Method: Thirty type 2 diabetic patients were included in the present randomized, controlled, double-blind, cross-over study. Subjects received DSF and isocaloric SF as a bolus administration of 400 mL while continuing their anti-diabetic medications. Venous blood samples were collected and analyzed to assess plasma glucose levels at pre- and at 30, 60, 90, 120, and 180 min post-administration of the formulas. Results: Postprandial glucose profiles were significantly lower with DSF compared to SF administration determined as a mean glucose concentration at 2-hour post-administration. The glucose area under the curve (AUC) after DSF consumption was 33% lower than the AUC after SF consumption, p<0.001. Conclusion: Use of DSF resulted in a significantly lower postprandial rise in plasma glucose concentrations than using SF. It should be the preferred option in diabetic patients who need nutritional support.
format Journal
author Supawan Buranapin
Sanguansak Siangruangsang
Vipawan Chantapanich
Natavuth Hengjeerajarus
author_facet Supawan Buranapin
Sanguansak Siangruangsang
Vipawan Chantapanich
Natavuth Hengjeerajarus
author_sort Supawan Buranapin
title The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients
title_short The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients
title_full The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients
title_fullStr The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients
title_full_unstemmed The comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 DM patients
title_sort comparative study of diabetic specific formula and standard formula on postprandial plasma glucose control in type 2 dm patients
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84904738909&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53780
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