HIV multi-drug resistance at first-line antiretroviral failure and subsequent virological response in Asia

• Main Authors: Awachana Jiamsakul, Somnuek Sungkanuparph, Matthew Law, Rami Kantor, Jutarat Praparattanapan, Patrick C.K. Li, Praphan Phanuphak, Tuti Merati, Winai Ratanasuwan, Christopher K.C. Lee, Rossana Ditangco, Mahiran Mustafa, Thida Singtoroj, Sasisopin Kiertiburanakul
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907420198&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53860
• Institution: Chiang Mai University

Introduction: First-line antiretroviral therapy (ART) failure often results from the development of resistance-associated mutations (RAMs). Three patterns, including thymidine analogue mutations (TAMs), 69 Insertion (69Ins) and the Q151M complex, are associated with resistance to multiple-nucleoside...