Kidney biomarkers in MCPA-induced acute kidney injury in rats: Reduced clearance enhances early biomarker performance

• المؤلفون الرئيسيون: Klintean Wunnapuk, Xin Liu, Glenda C. Gobe, Zoltan H. Endre, Philip W. Peake, Jeffrey E. Grice, Michael S. Roberts, Nicholas A. Buckley
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84893844954&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53884
• المؤسسة: Chiang Mai University

For improved early detection and assessment of severe acute kidney damage following accidental or intentional ingestion of the herbicide MCPA, we compared a panel of 14 novel kidney injury biomarkers with plasma creatinine. Male Wistar rats received four different oral doses of MCPA and plasma and u...