Bioactivity-guided separation of the active compounds in acacia pennata responsible for the prevention of Alzheimer's disease

• Main Authors: Pattamapan Lomarat, Sirirat Chancharunee, Natthinee Anantachoke, Worawan Kitphati, Kittisak Sripha, Nuntavan Bunyapraphatsara
• Format: Journal
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84945999798&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54049
• Institution: Chiang Mai University

The objective of this study was to evaluate the health benefits of plants used in Thai food, specifically Acacia pennata Willd., in Alzheimer's prevention. A. pennata twigs strongly inhibited β-amyloid aggregation. Bioactivity-guided separation of the active fractions yielded six known compound...