TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media

• Main Authors: Sirawit Wet-Osot, Wong Phakhodee, Mookda Pattarawarapan
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84947599657&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54096
• Institution: Chiang Mai University

© 2015 Elsevier Ltd. All rights reserved. The synthesis of N-acylbenzotriazoles has been demonstrated by the 2,4,6-trichloro-1,3,5-triazine (TCT)-mediated condensation of carboxylic acids with 1H-benzotriazole in aqueous media. In saturated aqueous sodium bicarbonate, TCT was found to be relatively...