Effects of low molecular weight hyaluronan combined with carprofen on canine osteoarthritis articular chondrocytes and cartilage explants in vitro

• Main Authors: Thippaporn Euppayo, Puntita Siengdee, Kittisak Buddhachat, Waranee Pradit, Nawarat Viriyakhasem, Siriwadee Chomdej, Siriwan Ongchai, Yasuji Harada, Korakot Nganvongpanit
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84942200275&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54118
• Institution: Chiang Mai University

© 2015, The Society for In Vitro Biology. Intra-articular injection with non-steroidal anti-inflammatory drugs (NSAIDs) is used to treat inflammatory joint disease, but the side effects of NSAIDs include chondrotoxicity. Hyaluronan has shown positive effects on chondrocytes by reducing apoptosis and...