Binding specificity of polypeptide substrates in NS2B/NS3pro serine protease of dengue virus type 2: A molecular dynamics Study

• Main Authors: Pathumwadee Yotmanee, Thanyada Rungrotmongkol, Kanin Wichapong, Sy Bing Choi, Habibah A. Wahab, Nawee Kungwan, Supot Hannongbua
• Format: Journal
• Published: 2018
• Subjects: Chemistry; Computer Science; Materials Science
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84935917965&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54289
• Institution: Chiang Mai University

© 2015 Elsevier Inc. All rights reserved. The pathogenic dengue virus (DV) is a growing global threat, particularly in South East Asia, for which there is no specific treatment available. The virus possesses a two-component (NS2B/NS3) serine protease that cleaves the viral precursor proteins. Here,...