HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study

© 2015 Colby D et al. Introduction: Pre-exposure prophylaxis (PrEP) is recommended by the World Health Organization as an effective method of HIV prevention for individuals at risk for infection. In this paper, we describe the unique role that Thailand has played in the global effort to combat the H...

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Main Authors: Donn Colby, Kriengkrai Srithanaviboonchai, Suphak Vanichseni, Sumet Ongwandee, Nittaya Phanuphak, Michael Martin, Kachit Choopanya, Suwat Chariyalertsak, Frits Van Griensven
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Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/54708
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-547082018-09-04T10:21:25Z HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study Donn Colby Kriengkrai Srithanaviboonchai Suphak Vanichseni Sumet Ongwandee Nittaya Phanuphak Michael Martin Kachit Choopanya Suwat Chariyalertsak Frits Van Griensven Medicine © 2015 Colby D et al. Introduction: Pre-exposure prophylaxis (PrEP) is recommended by the World Health Organization as an effective method of HIV prevention for individuals at risk for infection. In this paper, we describe the unique role that Thailand has played in the global effort to combat the HIV epidemic, including its role in proving the efficacy of PrEP, and discuss the opportunities and challenges of implementing PrEP in a middle-income country. Discussion: Thailand was one of the first countries in the world to successfully reverse a generalized HIV epidemic. Despite this early success, HIV prevalence has remained high among people who inject drugs and has surged among men who have sex with men (MSM) and transgender women (TGW). Two pivotal trials that showed that the use of oral antiretroviral medication as PrEP can reduce HIV transmission were conducted partially or entirely at Thai sites. Demonstration projects of PrEP, as well as clinical trials of alternative PrEP regimens, began or will begin in 2014-2015 in Thailand and will provide additional data and experience on how to best implement PrEP for high-risk individuals in the community. Financing of drug costs, the need for routine laboratory monitoring and lack of awareness about PrEP among at-risk groups all present challenges to the wider implementation of PrEP for HIV prevention in Thailand. Conclusions: Although significant challenges to wider use remain, PrEP holds promise as a safe and highly effective method to be used as part of a combined HIV prevention strategy for MSM and TGW in Thailand. 2018-09-04T10:21:25Z 2018-09-04T10:21:25Z 2015-07-20 Journal 17582652 2-s2.0-84938249797 10.7448/IAS.18.4.19953 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938249797&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54708
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Donn Colby
Kriengkrai Srithanaviboonchai
Suphak Vanichseni
Sumet Ongwandee
Nittaya Phanuphak
Michael Martin
Kachit Choopanya
Suwat Chariyalertsak
Frits Van Griensven
HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study
description © 2015 Colby D et al. Introduction: Pre-exposure prophylaxis (PrEP) is recommended by the World Health Organization as an effective method of HIV prevention for individuals at risk for infection. In this paper, we describe the unique role that Thailand has played in the global effort to combat the HIV epidemic, including its role in proving the efficacy of PrEP, and discuss the opportunities and challenges of implementing PrEP in a middle-income country. Discussion: Thailand was one of the first countries in the world to successfully reverse a generalized HIV epidemic. Despite this early success, HIV prevalence has remained high among people who inject drugs and has surged among men who have sex with men (MSM) and transgender women (TGW). Two pivotal trials that showed that the use of oral antiretroviral medication as PrEP can reduce HIV transmission were conducted partially or entirely at Thai sites. Demonstration projects of PrEP, as well as clinical trials of alternative PrEP regimens, began or will begin in 2014-2015 in Thailand and will provide additional data and experience on how to best implement PrEP for high-risk individuals in the community. Financing of drug costs, the need for routine laboratory monitoring and lack of awareness about PrEP among at-risk groups all present challenges to the wider implementation of PrEP for HIV prevention in Thailand. Conclusions: Although significant challenges to wider use remain, PrEP holds promise as a safe and highly effective method to be used as part of a combined HIV prevention strategy for MSM and TGW in Thailand.
format Journal
author Donn Colby
Kriengkrai Srithanaviboonchai
Suphak Vanichseni
Sumet Ongwandee
Nittaya Phanuphak
Michael Martin
Kachit Choopanya
Suwat Chariyalertsak
Frits Van Griensven
author_facet Donn Colby
Kriengkrai Srithanaviboonchai
Suphak Vanichseni
Sumet Ongwandee
Nittaya Phanuphak
Michael Martin
Kachit Choopanya
Suwat Chariyalertsak
Frits Van Griensven
author_sort Donn Colby
title HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study
title_short HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study
title_full HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study
title_fullStr HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study
title_full_unstemmed HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study
title_sort hiv pre-exposure prophylaxis and health and community systems in the global south: thailand case study
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938249797&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/54708
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