Plasma and Intracellular Pharmacokinetics of Tenofovir Disoproxil Fumarate 300 mg Every 48 Hours vs 150 mg Once Daily in HIV-Infected Adults with Moderate Renal Function Impairment

• Main Authors: Tim R. Cressey, Anchalee Avihingsanon, Guttiga Halue, Prattana Leenasirimakul, Pra Ornsuda Sukrakanchana, Yardpiroon Tawon, Nirattiya Jaisieng, Gonzague Jourdain, Anthony T. Podany, Courtney V. Fletcher, Virat Klinbuayaem, Chureeratana Bowonwatanuwong
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938634555&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54814
• Institution: Chiang Mai University

© 2015 The Author 2015. Background. The approved tenofovir disoproxil fumarate (TDF) dose of 300 mg every 48 hours for adults with moderate renal impairment is often confusing and inconvenient. Using a new TDF formulation, we compared the pharmacokinetics of the standard dose with a dose of 150 mg o...