Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand

Copyright © 2015. ScienceAsia. Nucleotide sequences of the mitochondrial DNA hypervariable region 2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 p...

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Main Authors:	Chaiwat Kriengchutima, Nadchanok Rodrussamee, Wibhu Kutanan, Jatupol Kampuansai
格式:	雜誌
出版:	2018
主題:	Multidisciplinary
在線閱讀:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938857878&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54914
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機構:	Chiang Mai University

id	th-cmuir.6653943832-54914
record_format	dspace
spelling	th-cmuir.6653943832-549142018-09-04T10:28:04Z Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand Chaiwat Kriengchutima Nadchanok Rodrussamee Wibhu Kutanan Jatupol Kampuansai Multidisciplinary Copyright © 2015. ScienceAsia. Nucleotide sequences of the mitochondrial DNA hypervariable region 2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 polymorphic sites, and 52 different sequence types were observed. The HVR2 possessed lower polymorphism than HVR1 of the same populations. However, when the two regions were combined, the discrimination power increased and could distinguish most of the Tai populations as well as separate the Tai from the neighbouring Mon-Khmer speaking populations. The Tai showed fewer genetic differences than those of the Mon-Khmer. This might have been a result of the admixture process across the Tai ethnic groups. The increasing of genetic polymorphism and discrimination power of the combined HVR1 and 2 data would enhance the accuracy and efficiency of personal and ethnicity identifications. 2018-09-04T10:28:04Z 2018-09-04T10:28:04Z 2015-01-01 Journal 15131874 2-s2.0-84938857878 10.2306/scienceasia1513-1874.2015.41.108 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938857878&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54914
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Multidisciplinary
spellingShingle	Multidisciplinary Chaiwat Kriengchutima Nadchanok Rodrussamee Wibhu Kutanan Jatupol Kampuansai Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
description	Copyright © 2015. ScienceAsia. Nucleotide sequences of the mitochondrial DNA hypervariable region 2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 polymorphic sites, and 52 different sequence types were observed. The HVR2 possessed lower polymorphism than HVR1 of the same populations. However, when the two regions were combined, the discrimination power increased and could distinguish most of the Tai populations as well as separate the Tai from the neighbouring Mon-Khmer speaking populations. The Tai showed fewer genetic differences than those of the Mon-Khmer. This might have been a result of the admixture process across the Tai ethnic groups. The increasing of genetic polymorphism and discrimination power of the combined HVR1 and 2 data would enhance the accuracy and efficiency of personal and ethnicity identifications.
format	Journal
author	Chaiwat Kriengchutima Nadchanok Rodrussamee Wibhu Kutanan Jatupol Kampuansai
author_facet	Chaiwat Kriengchutima Nadchanok Rodrussamee Wibhu Kutanan Jatupol Kampuansai
author_sort	Chaiwat Kriengchutima
title	Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_short	Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_full	Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_fullStr	Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_full_unstemmed	Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_sort	increasing the discrimination power of a mitochondrial dna control region by using hypervariable region 2 polymorphisms, as illustrated in tai populations of northern thailand
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938857878&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54914
_version_	1681424408764219392

Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand

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