Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand

Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand

Copyright © 2015. ScienceAsia. Nucleotide sequences of the mitochondrial DNA hypervariable region 2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 p...

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Main Authors: Chaiwat Kriengchutima, Nadchanok Rodrussamee, Wibhu Kutanan, Jatupol Kampuansai
Format: Journal
Published: 2018
Subjects:
Multidisciplinary
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/54914
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-549142018-09-04T10:28:04Z Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand Chaiwat Kriengchutima Nadchanok Rodrussamee Wibhu Kutanan Jatupol Kampuansai Multidisciplinary Copyright © 2015. ScienceAsia. Nucleotide sequences of the mitochondrial DNA hypervariable region 2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 polymorphic sites, and 52 different sequence types were observed. The HVR2 possessed lower polymorphism than HVR1 of the same populations. However, when the two regions were combined, the discrimination power increased and could distinguish most of the Tai populations as well as separate the Tai from the neighbouring Mon-Khmer speaking populations. The Tai showed fewer genetic differences than those of the Mon-Khmer. This might have been a result of the admixture process across the Tai ethnic groups. The increasing of genetic polymorphism and discrimination power of the combined HVR1 and 2 data would enhance the accuracy and efficiency of personal and ethnicity identifications. 2018-09-04T10:28:04Z 2018-09-04T10:28:04Z 2015-01-01 Journal 15131874 2-s2.0-84938857878 10.2306/scienceasia1513-1874.2015.41.108 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938857878&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54914
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Multidisciplinary
spellingShingle Multidisciplinary
Chaiwat Kriengchutima
Nadchanok Rodrussamee
Wibhu Kutanan
Jatupol Kampuansai
Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
description Copyright © 2015. ScienceAsia. Nucleotide sequences of the mitochondrial DNA hypervariable region 2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 polymorphic sites, and 52 different sequence types were observed. The HVR2 possessed lower polymorphism than HVR1 of the same populations. However, when the two regions were combined, the discrimination power increased and could distinguish most of the Tai populations as well as separate the Tai from the neighbouring Mon-Khmer speaking populations. The Tai showed fewer genetic differences than those of the Mon-Khmer. This might have been a result of the admixture process across the Tai ethnic groups. The increasing of genetic polymorphism and discrimination power of the combined HVR1 and 2 data would enhance the accuracy and efficiency of personal and ethnicity identifications.
format Journal
author Chaiwat Kriengchutima
Nadchanok Rodrussamee
Wibhu Kutanan
Jatupol Kampuansai
author_facet Chaiwat Kriengchutima
Nadchanok Rodrussamee
Wibhu Kutanan
Jatupol Kampuansai
author_sort Chaiwat Kriengchutima
title Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_short Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_full Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_fullStr Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_full_unstemmed Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region 2 polymorphisms, as illustrated in Tai populations of Northern Thailand
title_sort increasing the discrimination power of a mitochondrial dna control region by using hypervariable region 2 polymorphisms, as illustrated in tai populations of northern thailand
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938857878&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/54914
_version_ 1681424408764219392

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