A new cytotoxic clerodane diterpene from casearia graveolens twigs

The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 show...

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Main Authors:	Pornphimol Meesakul, Thunwadee Ritthiwigrom, Sarot Cheenpracha, Tawanun Sripisut, Wisanu Maneerat, Theeraphan MacHan, Surat Laphookhieo
Format:	Journal
Published:	2018
Subjects:	Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55050
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-55050
record_format	dspace
spelling	th-cmuir.6653943832-550502018-09-05T03:12:28Z A new cytotoxic clerodane diterpene from casearia graveolens twigs Pornphimol Meesakul Thunwadee Ritthiwigrom Sarot Cheenpracha Tawanun Sripisut Wisanu Maneerat Theeraphan MacHan Surat Laphookhieo Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively. 2018-09-05T02:51:19Z 2018-09-05T02:51:19Z 2016-01-23 Journal 15559475 1934578X 2-s2.0-84973408865 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55050
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics Pornphimol Meesakul Thunwadee Ritthiwigrom Sarot Cheenpracha Tawanun Sripisut Wisanu Maneerat Theeraphan MacHan Surat Laphookhieo A new cytotoxic clerodane diterpene from casearia graveolens twigs
description	The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively.
format	Journal
author	Pornphimol Meesakul Thunwadee Ritthiwigrom Sarot Cheenpracha Tawanun Sripisut Wisanu Maneerat Theeraphan MacHan Surat Laphookhieo
author_facet	Pornphimol Meesakul Thunwadee Ritthiwigrom Sarot Cheenpracha Tawanun Sripisut Wisanu Maneerat Theeraphan MacHan Surat Laphookhieo
author_sort	Pornphimol Meesakul
title	A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_short	A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_full	A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_fullStr	A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_full_unstemmed	A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_sort	new cytotoxic clerodane diterpene from casearia graveolens twigs
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55050
_version_	1681424433844060160

A new cytotoxic clerodane diterpene from casearia graveolens twigs

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