Susceptibility of inhibitors against 3C protease of coxsackievirus A16 and enterovirus A71 causing hand, foot and mouth disease: A molecular dynamics study

• Main Authors: W. Jetsadawisut, B. Nutho, A. Meeprasert, T. Rungrotmongkol, N. Kungwan, P. Wolschann, S. Hannongbua
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84988473760&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55123
• Institution: Chiang Mai University

© 2016 Elsevier B.V. Hand foot and mouth disease (HFMD) epidemic has occurred in many countries. Coxsackievirus A16 (CV-A16) and Enterovirus A71 (EV-A71) are the main causes of HFMD. Up to now, there are no anti-HFMD drugs available. Rupintrivir, a broad-spectrum inhibitor, is a drug candidate for H...