Melatonin improves methamphetamine-induced blood brain barrier impairment through NADPH oxidase-2 in primary rat brain microvascular endothelium cells

• Main Authors: Pichaya Jumnongprakhon, Piyarat Govitrapong, Chainarong Tocharus, Jiraporn Tocharus
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84976612023&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55155
• Institution: Chiang Mai University

© 2016 Elsevier B.V. Melatonin is a neurohormone and has high potent of antioxidant that is widely reported to be active against methamphetamine (METH)-induced toxicity to neuron, glial cells, and brain endothelial cells. However, the role of melatonin on the inflammatory responses which are mostly...