Overexpression of KH-type splicing regulatory protein regulates proliferation, migration, and implantation ability of osteosarcoma

• Main Authors: Dumnoensun Pruksakorn, Pimpisa Teeyakasem, Jeerawan Klangjorhor, Parunya Chaiyawat, Jongkolnee Settakorn, Penchatr Diskul-Na-Ayudthaya, Daranee Chokchaichamnankit, Peraphan Pothacharoen, Chantragan Srisomsap
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Medicine
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978516319&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55161
• 機構: Chiang Mai University

Osteosarcoma is a common malignant bone tumor in children and adolescents. The current 5-year survival rate is ~60% and that seems to be reaching a plateau. In order to improve treatment outcomes of osteosarcoma, a better understanding of tumorigenesis and underlying molecular mechanisms is required...