Expedient screening for HIV-1 protease inhibitors using a simplified immunochromatographic assay

• Main Authors: Kuntida Kitidee, Wannisa Khamaikawin, Weeraya Thongkum, Yardpiroon Tawon, Tim R. Cressey, Rachaneekorn Jevprasesphant, Watchara Kasinrerk, Chatchai Tayapiwatana
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84952837633&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55207
• Institution: Chiang Mai University

© 2015 Elsevier B.V. A colloidal gold-based immunochromatographic (IC) strip test was developed and validated for the detection of HIV-1 protease (HIV-PR) activity and inhibitory effect of HIV-PR inhibitors (PIs). It is a unique 'two-step' process requiring the combination of proteolysis o...