Effects of iron overload condition on liver toxicity and hepcidin/ferroportin expression in thalassemic mice

• Main Authors: Sirinart Kumfu, Siriporn C. Chattipakorn, Suthat Fucharoen, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84959284035&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55226
• Institution: Chiang Mai University

© 2016 Elsevier Inc. Aims Although iron-overload conditions can be found in β-thalassemic patients, resulting in cellular damage, particularly in the liver, the mechanism for this iron-mediated hepatic injury specifically in β-thalassemic (HT) mice is unclear. This study aimed to investigate the rol...