Ultrasound-assisted synthesis of substituted guanidines from thioureas

• Main Authors: Mookda Pattarawarapan, Subin Jaita, Sirilak Wangngae, Wong Phakhodee
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84975822864&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55229
• Institution: Chiang Mai University

© 2016 Elsevier Ltd Ultrasound-assisted synthesis of guanidine derivatives was developed using 2,4,6-trichloro-1,3,5-triazine as an inexpensive dehydrosulfurization reagent. Both 1,3-alkylaryl- and 1,3-diaryl-thioureas were rapidly converted into carbodiimides before subsequent reaction with aromati...