Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways

• Main Authors: Ratana Banjerdpongchai, Benjawan Wudtiwai, Patompong Khaw-on, Wasitta Rachakhom, Natthachai Duangnil, Prachya Kongtawelert
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84937622393&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55249
• Institution: Chiang Mai University

© 2015, The Author(s). Citrus seeds are full of phenolic compounds, such as flavonoids. The aims of this study were to identify the types of flavonoids in Citrus seed extracts, the cytotoxic effect, mode of cell death, and signaling pathway in human hepatic cancer HepG2 cells. The flavonoids contain...