p16 - a Possible Surrogate Marker for High-Risk Human Papillomaviruses in Oral Cancer?

• Main Authors: Thanun Sritippho, Surawut Pongsiriwet, Nirush Lertprasertsuke, Kittisak Buddhachat, Thanapat Sastraruji, Anak Iamaroon
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047591788&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55259
• Institution: Chiang Mai University

BACKGROUND: High-risk human papillomaviruses (HR-HPV), particularly types 16 and 18, have been found to play an important role in head and neck cancer, including oropharyngeal squamous cell carcinoma (OPSCC) and oral squamous cell carcinoma (OSCC). p16, a cell cycle inhibitor, has been postulated as...