A convenient synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones under solvent-assisted grinding

© 2016 Elsevier Ltd A facile and effective approach for the synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones has been developed. Under solvent-assisted grinding in the presence of 2,4,6-trichloro-1,3,5-triazine, catalytic triphenylphosphine, and sodium carbonate, dehydration–condensation of hippur...

Full description

Saved in:
Bibliographic Details
Main Authors: Mookda Pattarawarapan, Subin Jaita, Wong Phakhodee
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84975853310&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/55262
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
Description
Summary:© 2016 Elsevier Ltd A facile and effective approach for the synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones has been developed. Under solvent-assisted grinding in the presence of 2,4,6-trichloro-1,3,5-triazine, catalytic triphenylphosphine, and sodium carbonate, dehydration–condensation of hippuric acid with aromatic aldehydes proceeded rapidly within minutes at room temperature to afford the products in good to excellent yields.