Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles

© 2016 Elsevier Ltd A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph3P–I2system in the presence of triethylamine as a desulfurization agent, monothioureas pr...

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Main Authors:	Wong Phakhodee, Chuthamat Duangkamol, Nittaya Wiriya, Mookda Pattarawarapan
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994322327&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55263
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-55263
record_format	dspace
spelling	th-cmuir.6653943832-552632018-09-05T03:12:37Z Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles Wong Phakhodee Chuthamat Duangkamol Nittaya Wiriya Mookda Pattarawarapan Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics © 2016 Elsevier Ltd A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph3P–I2system in the presence of triethylamine as a desulfurization agent, monothioureas prepared in situ from the reaction of bis-nucleophiles with isothiocyanates underwent rapid cyclization to afford a variety of N-heterocyclic compounds in good to excellent yields under mild conditions. 2018-09-05T02:53:46Z 2018-09-05T02:53:46Z 2016-01-01 Journal 18733581 00404039 2-s2.0-84994322327 10.1016/j.tetlet.2016.10.060 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994322327&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55263
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Wong Phakhodee Chuthamat Duangkamol Nittaya Wiriya Mookda Pattarawarapan Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
description	© 2016 Elsevier Ltd A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph3P–I2system in the presence of triethylamine as a desulfurization agent, monothioureas prepared in situ from the reaction of bis-nucleophiles with isothiocyanates underwent rapid cyclization to afford a variety of N-heterocyclic compounds in good to excellent yields under mild conditions.
format	Journal
author	Wong Phakhodee Chuthamat Duangkamol Nittaya Wiriya Mookda Pattarawarapan
author_facet	Wong Phakhodee Chuthamat Duangkamol Nittaya Wiriya Mookda Pattarawarapan
author_sort	Wong Phakhodee
title	Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_short	Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_full	Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_fullStr	Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_full_unstemmed	Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_sort	ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994322327&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55263
_version_	1681424473355452416

Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles

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