Host stromal versican is essential for cancer-associated fibroblast function to inhibit cancer growth

• Main Authors: Kanda Fanhchaksai, Futoshi Okada, Naoko Nagai, Peraphan Pothacharoen, Prachya Kongtawelert, Sonoko Hatano, Shinji Makino, Tomoyuki Nakamura, Hideto Watanabe
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84955705245&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55312
• Institution: Chiang Mai University

© 2015 UICC. The stroma provides a microenvironment that regulates tumor cell behavior. The extracellular matrix (ECM) has long been recognized to be important in tumor cell behavior, and previous studies have revealed the impact of individual matrix molecules on tumor progression. Although several...