Role of R292K mutation in influenza H7N9 neuraminidase toward oseltamivir susceptibility: MD and MM/PB(GB)SA study

• Main Authors: Jiraphorn Phanich, Thanyada Rungrotmongkol, Nawee Kungwan, Supot Hannongbua
• Format: Journal
• Published: 2018
• Subjects: Chemistry; Computer Science; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84990841546&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55438
• Institution: Chiang Mai University

© 2016, Springer International Publishing Switzerland. The H7N9 avian influenza virus is a novel re-assortment from at least four different strains of virus. Neuraminidase, which is a glycoprotein on the surface membrane, has been the target for drug treatment. However, some H7N9 strains that have b...