A sample size calculation of Bayesian design for superiority trials with rare events

• المؤلفون الرئيسيون: Patumrat Sripan, Lily Ingsrisawang, Billy Amzal, Sophie Le Ccur, Tim R. Cressey, Marc Lallemant, Salk Urien
• التنسيق: وقائع المؤتمر
• منشور في: 2018
• الموضوعات: Computer Science
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978708523&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55612
• المؤسسة: Chiang Mai University

Traditional approaches used in sample calculation for superiority trials comparing two low proportions usually provide very large sample sizes. Furthermore, such calculations may be inaccurate due to asymptotic normality that is often assumed but may not hold in such cases. Bayesian approach could r...