Additive effect of knockdown resistance mutations, S989P, V1016G and F1534C, in a heterozygous genotype conferring pyrethroid resistance in Aedes aegypti in Thailand

• Main Authors: Suriya Plernsub, Jassada Saingamsook, Jintana Yanola, Nongkran Lumjuan, Pongsri Tippawangkosol, Kom Sukontason, Catherine Walton, Pradya Somboon
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84979582011&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/55891
• Institution: Chiang Mai University

© 2016 The Author(s). Background: Mutation in the voltage-gated sodium channel gene that results in knockdown resistance (kdr), is a major mechanism of pyrethroid resistance in several mosquito species. In Aedes aegypti, V1016G (occurring with and without S989P) and F1534C mutations are common and w...