What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?

© 2016 Elsevier Ireland Ltd Objectives Acute otitis media (AOM) is a common infectious disease in children. Data regarding the distribution of causative pathogens are not universal. Tympanic perforation due to AOM may occur in 5–30% of AOM patients. The causative pathogens for AOM with tympanic perf...

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Main Authors: Nuntigar Sonsuwan, Patcharin Watcharinyanon, Kittisak Sawanyawisuth
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/56023
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spelling th-cmuir.6653943832-560232018-09-05T03:07:55Z What are the leading causative pathogens in acute otitis media with tympanic membrane perforation? Nuntigar Sonsuwan Patcharin Watcharinyanon Kittisak Sawanyawisuth Medicine © 2016 Elsevier Ireland Ltd Objectives Acute otitis media (AOM) is a common infectious disease in children. Data regarding the distribution of causative pathogens are not universal. Tympanic perforation due to AOM may occur in 5–30% of AOM patients. The causative pathogens for AOM with tympanic perforation are limited. Methods This was a prospective study conducted at the Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand. All consecutive children diagnosed as having AOM with tympanic perforation were enrolled. The age of the eligible patients was between 3 months and 5 years. Pus from the middle ear of each patient was swabbed and tested for culture/sensitivity. Results There were 40 eligible patients diagnosed with AOM with tympanic perforation in this study. The mean age of all patients was 24.3 months and the patients were predominantly male (26 male; 65.0%). None of these patients received S. pneumoniae or H. influenzae vaccination. All specimens were culture positive (100%) and 13 organisms were identified. There were 53 identified pathogens; the most common pathogen was H. influenzae (19 times or 35.8%), followed by Staphylococcus aureus (14 times or 26.4%). H. influenzae was 100% sensitive to chloramphenicol, amoxicilllin/clavulanic acid, cefotaxime, and ciprofloxacin, while S. aureus was also 100% sensitive to oxacillin, vancomycin, and fusidic acid. Conclusions The two most common pathogens for AOM with tympanic perforation were H. influenzae and Staphylococcus aureus. Both pathogens were mostly sensitive to antibiotics. 2018-09-05T03:07:55Z 2018-09-05T03:07:55Z 2016-11-01 Journal 18728464 01655876 2-s2.0-84984856769 10.1016/j.ijporl.2016.08.021 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84984856769&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56023
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Nuntigar Sonsuwan
Patcharin Watcharinyanon
Kittisak Sawanyawisuth
What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
description © 2016 Elsevier Ireland Ltd Objectives Acute otitis media (AOM) is a common infectious disease in children. Data regarding the distribution of causative pathogens are not universal. Tympanic perforation due to AOM may occur in 5–30% of AOM patients. The causative pathogens for AOM with tympanic perforation are limited. Methods This was a prospective study conducted at the Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand. All consecutive children diagnosed as having AOM with tympanic perforation were enrolled. The age of the eligible patients was between 3 months and 5 years. Pus from the middle ear of each patient was swabbed and tested for culture/sensitivity. Results There were 40 eligible patients diagnosed with AOM with tympanic perforation in this study. The mean age of all patients was 24.3 months and the patients were predominantly male (26 male; 65.0%). None of these patients received S. pneumoniae or H. influenzae vaccination. All specimens were culture positive (100%) and 13 organisms were identified. There were 53 identified pathogens; the most common pathogen was H. influenzae (19 times or 35.8%), followed by Staphylococcus aureus (14 times or 26.4%). H. influenzae was 100% sensitive to chloramphenicol, amoxicilllin/clavulanic acid, cefotaxime, and ciprofloxacin, while S. aureus was also 100% sensitive to oxacillin, vancomycin, and fusidic acid. Conclusions The two most common pathogens for AOM with tympanic perforation were H. influenzae and Staphylococcus aureus. Both pathogens were mostly sensitive to antibiotics.
format Journal
author Nuntigar Sonsuwan
Patcharin Watcharinyanon
Kittisak Sawanyawisuth
author_facet Nuntigar Sonsuwan
Patcharin Watcharinyanon
Kittisak Sawanyawisuth
author_sort Nuntigar Sonsuwan
title What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
title_short What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
title_full What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
title_fullStr What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
title_full_unstemmed What are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
title_sort what are the leading causative pathogens in acute otitis media with tympanic membrane perforation?
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84984856769&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56023
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