Prevention of mother-to-child transmission of hepatitis B virus: A phase III, placebo-controlled, double-blind, randomized clinical trial to assess the efficacy and safety of a short course of tenofovir disoproxil fumarate in women with hepatitis B virus e-antigen

• Main Authors: Gonzague Jourdain, Nicole Ngo-Giang-Huong, Tim R. Cressey, Lei Hua, Linda Harrison, Camlin Tierney, Nicolas Salvadori, Luc Decker, Patrinee Traisathit, Wasna Sirirungsi, Woottichai Khamduang, Chureeratana Bowonwatanuwong, Thanyawee Puthanakit, George K. Siberry, Diane Heather Watts, Trudy V. Murphy, Jullapong Achalapong, Suchat Hongsiriwon, Virat Klinbuayaem, Satawat Thongsawat, Raymond T. Chung, Stanislas Pol, Nantasak Chotivanich
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84981186408&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56096
• Institution: Chiang Mai University

© 2016 The Author(s). Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. In Thailand, 6-7 % of adults are chronically infected with HBV. The risk of mother-to-child transmission (MTCT) of HBV has been estimated to be about 12 % when mothers have a hig...