Estrogen and DPP4 inhibitor, but not metformin, exert cardioprotection via attenuating cardiac mitochondrial dysfunction in obese insulin-resistant and estrogen-deprived female rats

Estrogen and DPP4 inhibitor, but not metformin, exert cardioprotection via attenuating cardiac mitochondrial dysfunction in obese insulin-resistant and estrogen-deprived female rats

© 2016 by The North American Menopause Society. Objective: Cardiac function was markedly compromised in obese insulin-resistant and estrogen-deprived rats. Metformin and dipeptidyl peptidase-4 inhibitor (vildagliptin) were reported to improve cardiac function in insulinresistant rats. Their effects...

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Main Authors: Sivaporn Sivasinprasasn, Piangkwan Sa-Nguanmoo, Wanpitak Pongkan, Wasana Pratchayasakul, Siriporn C. Chattipakorn, Nipon Chattipakorn
Format: Journal
Published: 2018
Subjects:
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84975484640&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56109
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Institution: Chiang Mai University

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