Ex vivo model exhibits protective effects of sesamin against destruction of cartilage induced with a combination of tumor necrosis factor-alpha and oncostatin M

• Main Authors: Manatsanan Khansai, Kanchanit Boonmaleerat, Peraphan Pothacharoen, Thanyaluck Phitak, Prachya Kongtawelert
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84979650114&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56111
• Institution: Chiang Mai University

© 2016 The Author(s). Background: Rheumatoid arthritis (RA) is an autoimmune disease associated with chronic inflammatory arthritis. TNF-α and OSM are pro-inflammatory cytokines that play a key role in RA progression. Thus, reducing the effects of both cytokines is practical in order to relieve the...