Acute bone infarction: a rare complication in thalassemia

Acute bone infarction: a rare complication in thalassemia

© 2016, ISS. Acute bone infarction is a well-described complication in sickle cell hemoglobinopathy but it is rarely reported in patients with thalassemia. This report describes an 18-year-old man with homozygous β-thalassemia presenting with a fever and severe acute bilateral ankle pain. The acute...

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Main Authors: Thanat Kanthawang, Nuttaya Pattamapaspong, Worawit Louthrenoo
Format: Journal
Published: 2018
Subjects:
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964199973&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56116
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-561162018-09-05T03:09:07Z Acute bone infarction: a rare complication in thalassemia Thanat Kanthawang Nuttaya Pattamapaspong Worawit Louthrenoo Medicine © 2016, ISS. Acute bone infarction is a well-described complication in sickle cell hemoglobinopathy but it is rarely reported in patients with thalassemia. This report describes an 18-year-old man with homozygous β-thalassemia presenting with a fever and severe acute bilateral ankle pain. The acute onset of severe pain and fever were clinical mimics of infectious arthritis and osteomyelitis. Magnetic resonance imaging revealed acute bone infarction in the meta-diaphysis of bilateral tibias presenting as central unenhanced devitalized bone with T1-high signal intensity fluid in the subperiosteum and soft tissue. Characteristic imaging features are discussed, emphasizing the benefit of fat suppression pre-and post-intravenous gadolinium T1-weighted images. The etiologies of bone infarction in thalassemia are reviewed. 2018-09-05T03:09:07Z 2018-09-05T03:09:07Z 2016-07-01 Journal 14322161 03642348 2-s2.0-84964199973 10.1007/s00256-016-2387-6 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964199973&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56116
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Thanat Kanthawang
Nuttaya Pattamapaspong
Worawit Louthrenoo
Acute bone infarction: a rare complication in thalassemia
description © 2016, ISS. Acute bone infarction is a well-described complication in sickle cell hemoglobinopathy but it is rarely reported in patients with thalassemia. This report describes an 18-year-old man with homozygous β-thalassemia presenting with a fever and severe acute bilateral ankle pain. The acute onset of severe pain and fever were clinical mimics of infectious arthritis and osteomyelitis. Magnetic resonance imaging revealed acute bone infarction in the meta-diaphysis of bilateral tibias presenting as central unenhanced devitalized bone with T1-high signal intensity fluid in the subperiosteum and soft tissue. Characteristic imaging features are discussed, emphasizing the benefit of fat suppression pre-and post-intravenous gadolinium T1-weighted images. The etiologies of bone infarction in thalassemia are reviewed.
format Journal
author Thanat Kanthawang
Nuttaya Pattamapaspong
Worawit Louthrenoo
author_facet Thanat Kanthawang
Nuttaya Pattamapaspong
Worawit Louthrenoo
author_sort Thanat Kanthawang
title Acute bone infarction: a rare complication in thalassemia
title_short Acute bone infarction: a rare complication in thalassemia
title_full Acute bone infarction: a rare complication in thalassemia
title_fullStr Acute bone infarction: a rare complication in thalassemia
title_full_unstemmed Acute bone infarction: a rare complication in thalassemia
title_sort acute bone infarction: a rare complication in thalassemia
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964199973&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56116
_version_ 1681424631894900736

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