Association of Neuroprotective Effect of Di-O-Demethylcurcumin on Aβ<inf>25–35</inf>-Induced Neurotoxicity with Suppression of NF-κB and Activation of Nrf2

• Main Authors: Decha Pinkaew, Chatchawan Changtam, Chainarong Tocharus, Piyarat Govitrapong, Pichaya Jumnongprakhon, Apichart Suksamrarn, Jiraporn Tocharus
• Format: Journal
• Published: 2018
• Subjects: Neuroscience; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84953347339&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56258
• Institution: Chiang Mai University

© 2015, Springer Science+Business Media New York. Amyloid-β peptides (Aβ), a major component of senile plaques, play an important role in the development and progression of Alzheimer’s disease. Several lines of evidence have demonstrated that Aβ-induced neuronal death is mediated by oxidative stress...