Vagus Nerve Stimulation Exerts the Neuroprotective Effects in Obese-Insulin Resistant Rats, Leading to the Improvement of Cognitive Function

• Main Authors: Titikorn Chunchai, Bencharunan Samniang, Jirapas Sripetchwandee, Hiranya Pintana, Wanpitak Pongkan, Sirinart Kumfu, Krekwit Shinlapawittayatorn, Bruce H. Kenknight, Nipon Chattipakorn, Siriporn C. Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84971318138&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56360
• Institution: Chiang Mai University

Vagus nerve stimulation (VNS) therapy was shown to improve peripheral insulin sensitivity. However, the effects of chronic VNS therapy on brain insulin sensitivity, dendritic spine density, brain mitochondrial function, apoptosis and cognition in obese-insulin resistant subjects have never been inve...