Computational screening of fatty acid synthase inhibitors against thioesterase domain

• Main Authors: Wanwisa Panman, Bodee Nutho, Supakarn Chamni, Supaporn Dokmaisrijan, Nawee Kungwan, Thanyada Rungrotmongkol
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85038030583&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56655
• 機構: Chiang Mai University

© 2017 Informa UK Limited, trading as Taylor & Francis Group Thioesterase (TE) domain of fatty acid synthase (FAS) is an attractive therapeutic target for design and development of anticancer drugs. In this present work, we search for the potential FAS inhibitors of TE domain from the ZINC dat...