Voltage-gated sodium channels assemble and gate as dimers
© 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation...
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th-cmuir.6653943832-566662018-09-05T03:52:21Z Voltage-gated sodium channels assemble and gate as dimers Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes Biochemistry, Genetics and Molecular Biology Chemistry Physics and Astronomy © 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation is conserved. 2018-09-05T03:28:40Z 2018-09-05T03:28:40Z 2017-12-01 Journal 20411723 2-s2.0-85037870387 10.1038/s41467-017-02262-0 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037870387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56666 |
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Biochemistry, Genetics and Molecular Biology Chemistry Physics and Astronomy |
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Biochemistry, Genetics and Molecular Biology Chemistry Physics and Astronomy Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes Voltage-gated sodium channels assemble and gate as dimers |
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© 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation is conserved. |
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Journal |
author |
Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes |
author_facet |
Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes |
author_sort |
Jérôme Clatot |
title |
Voltage-gated sodium channels assemble and gate as dimers |
title_short |
Voltage-gated sodium channels assemble and gate as dimers |
title_full |
Voltage-gated sodium channels assemble and gate as dimers |
title_fullStr |
Voltage-gated sodium channels assemble and gate as dimers |
title_full_unstemmed |
Voltage-gated sodium channels assemble and gate as dimers |
title_sort |
voltage-gated sodium channels assemble and gate as dimers |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037870387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56666 |
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