Early testosterone replacement attenuates intracellular calcium dyshomeostasis in the heart of testosterone-deprived male rats

• Main Authors: Punate Weerateerangkul, Krekwit Shinlapawittayatorn, Siripong Palee, Nattayaporn Apaijai, Siriporn C. Chattipakorn, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85027696915&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56672
• Institution: Chiang Mai University

© 2017 Elsevier Ltd Background Testosterone deficiency in elderly men increases the risk of cardiovascular disease. In bilateral orchiectomized (ORX) animals, impaired cardiac Ca2+regulation was observed, and this impairment could be improved by testosterone replacement, indicating the important rol...