Impaired osteogenic differentiation and enhanced cellular receptor of advanced glycation end products sensitivity in patients with type 2 diabetes

• Main Authors: Mattabhorn Phimphilai, Peraphan Pothacharoen, Prachya Kongtawelert, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84996533953&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56676
• Institution: Chiang Mai University

© 2016, The Japanese Society for Bone and Mineral Research and Springer Japan. Preclinical studies have demonstrated impaired osteoblast differentiation in type 2 diabetes (T2DM), which is related to skeletal accumulation of advanced glycation end products (AGEs). However, the role of AGE in osteobl...