Zn²⁺-dependent autocatalytic activity of the Bordetella pertussis CyaA-hemolysin

• Main Authors: Veerada Raksanoh, Lalida Shank, Panchika Prangkio, Mattayaus Yentongchai, Somsri Sakdee, Chompounoot Imtong, Chanan Angsuthanasombat
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85014098136&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56770
• Institution: Chiang Mai University

© 2017 Elsevier Inc. Proteolytic degradation of the ∼100-kDa isolated RTX (Repeat-in-ToXin) subdomain (CyaA-RTX) of the Bordetella pertussis CyaA-hemolysin (CyaA-Hly) was evidently detected upon solely-prolonged incubation. Here, a truncated CyaA-Hly fragment (CyaA-HP/BI) containing hydrophobic and...