Downregulation of extracellular matrix metalloproteinase inducer by scFv-M6-1B9 intrabody suppresses cervical cancer invasion through inhibition of urokinase-type plasminogen activator

• Main Authors: Tipattaraporn Panich, Khajornsak Tragoolpua, Supansa Pata, Chatchai Tayapiwatana, Nutjeera Intasai
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012237115&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56801
• Institution: Chiang Mai University

© Mary Ann Liebert, Inc. 2017. Overexpression of extracellular matrix metalloproteinase inducer (EMMPRIN) accelerates tumor invasion and metastasis via activation of matrix metalloproteinases (MMPs) and urokinase-type plasminogen activator (uPA) expression. The authors were interested in whether the...