Ph<inf>3</inf>P/I<inf>2</inf>-Mediated Synthesis of 3-Aryl-Substituted and 3,4-Disubstituted Coumarins
© Georg Thieme Verlag Stuttgart New York. Ph3P/I2-Et3N-mediated one-pot two-step esterification-cyclization toward 3-aryl coumarins and 3-aryl-4-methylcoumarins is reported. The reaction of a variety of aryl acetic acids containing steric or reactive group with 2-hydroxybenzaldehydes or 2′-hydroxyac...
محفوظ في:
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | دورية |
| منشور في: |
2018
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85011632872&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56989 |
| الوسوم: |
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| الملخص: | © Georg Thieme Verlag Stuttgart New York. Ph3P/I2-Et3N-mediated one-pot two-step esterification-cyclization toward 3-aryl coumarins and 3-aryl-4-methylcoumarins is reported. The reaction of a variety of aryl acetic acids containing steric or reactive group with 2-hydroxybenzaldehydes or 2′-hydroxyacetophenone proceeded smoothly at room temperature to afford the corresponding products in good to excellent yields using inexpensive and readily available reactants and reagents. |
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