Effect of Amino Acid Substitutions Within the V3 Region of HIV-1 CRF01-AE on Interaction with CCR5-Coreceptor

• Main Authors: Sayamon Hongjaisee, Martine Braibant, Francis Barin, Nicole Ngo-Giang-Huong, Wasna Sirirungsi, Tanawan Samleerat
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85028562764&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/57438
• Institution: Chiang Mai University

© Copyright 2017, Mary Ann Liebert, Inc. 2017. Specific amino acids within the V3 loop of HIV-1 CRF01-AE envelope glycoprotein that are involved in the interaction with CCR5/CXCR4 coreceptors, are not well characterized. We generated V3 mutants using polymerase chain reaction (PCR)-based site-direct...