Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents

Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents

Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-human immunodeficiency virus-coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their m...

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Main Authors: Linda Aurpibul, Pagakrong Lumbiganon, Rawiwan Hansudewechakul, Suparat Kanjanavanit, Torsak Bunupuradah, Pope Kosalaraksa, Pawinee Taeprasert, Thanyawee Puthanakit
Format: Journal
Published: 2018
Subjects:
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85007247655&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/57728
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Institution: Chiang Mai University
id th-cmuir.6653943832-57728
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spelling th-cmuir.6653943832-577282018-09-05T03:48:45Z Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents Linda Aurpibul Pagakrong Lumbiganon Rawiwan Hansudewechakul Suparat Kanjanavanit Torsak Bunupuradah Pope Kosalaraksa Pawinee Taeprasert Thanyawee Puthanakit Medicine Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-human immunodeficiency virus-coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their median age was 17.6 years, and duration of 3TC exposure was 7.3 years. Eleven patients (61%) achieved HBV DNA <60 IU/mL after 48 weeks on TDF and 3TC which was similar to adult studies, although hepatitis B surface antigen loss or hepatitis B envelope antigen seroconversion did not occur. 2018-09-05T03:48:45Z 2018-09-05T03:48:45Z 2017-04-01 Journal 15320987 08913668 2-s2.0-85007247655 10.1097/INF.0000000000001491 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85007247655&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/57728
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Linda Aurpibul
Pagakrong Lumbiganon
Rawiwan Hansudewechakul
Suparat Kanjanavanit
Torsak Bunupuradah
Pope Kosalaraksa
Pawinee Taeprasert
Thanyawee Puthanakit
Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
description Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-human immunodeficiency virus-coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their median age was 17.6 years, and duration of 3TC exposure was 7.3 years. Eleven patients (61%) achieved HBV DNA <60 IU/mL after 48 weeks on TDF and 3TC which was similar to adult studies, although hepatitis B surface antigen loss or hepatitis B envelope antigen seroconversion did not occur.
format Journal
author Linda Aurpibul
Pagakrong Lumbiganon
Rawiwan Hansudewechakul
Suparat Kanjanavanit
Torsak Bunupuradah
Pope Kosalaraksa
Pawinee Taeprasert
Thanyawee Puthanakit
author_facet Linda Aurpibul
Pagakrong Lumbiganon
Rawiwan Hansudewechakul
Suparat Kanjanavanit
Torsak Bunupuradah
Pope Kosalaraksa
Pawinee Taeprasert
Thanyawee Puthanakit
author_sort Linda Aurpibul
title Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
title_short Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
title_full Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
title_fullStr Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
title_full_unstemmed Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
title_sort response to tenofovir among lamivudine-experienced hepatitis b and hiv-coinfected adolescents
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85007247655&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/57728
_version_ 1681424932791123968

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